Engineering cell-cell interactions in cancer

We employ a quantitative approach that integrates microfluidics, systems biology modeling, and in vivo experiments to investigate the role of the tumor microenvironment on breast and ovarian cancer growth, metastasis and drug resistance.


The lab is growing and there are openings at the student, postdoc and research assistant levels. Our lab offers the opportunity to work at the forefront of cancer bioengineering, learn cutting edge techniques and collaborate with an interdisciplinary group of scientists and clinicians in the Cancer Center.

Video of invading breast carcinoma cells in a 3D microfluidic device (Zervantonakis et al)


September 2020:      Congratulations to Dorota for receiving the BiRM T32 and Matt for receiving the CATER                                     T32! 

August 2020:           Our lab welcomes Don as the new Postdoctoral Fellow in the lab. Welcome Don!

June, 25th 2020:      Congratulations to Dorota and Matt for passing their preliminary exams!

June, 23rd 2020:      Our lab welcomes two high school students: Tibo and Jonathan who will be working over                                the summer. Welcome Tibo and Jonothan!


June, 16th 2020:      Yannis is selected as a 2020 Hillman Early-Career Fellow for Innovative Cancer Research

June, 16th 2020:      Our lab is awarded a 1-year grant from Elsa Pardee Foundation to model metastatic                                        ovarian cancer microenvironment.

June, 1st 2020:        Our lab welcomes Rosy to the Bioengineering PhD program. Welcome Rosy!

May, 20th 2020:       Our lab welcomes Jacob and Ashlinn, BioE undergraduate students who will be working

                              remotely this summer. Welcome Jacob and Ashlinn!

Mar, 1st 2020:          New Nikon Ti-2E widefield live cell microscope installed: Microfluidic time-lapse imaging 

Feb, 01 & 21 2020:   Our lab presents posters at the 2020 ISB/BioE Recruitment events

Jan, 15th 2020:        New BioTek Imager Installed: Lots of time-lapse data to come!

Jan, 10th 2020:        Lia joins the lab as ChemE undergraduate student. Welcome Lia!

Nov, 10 2019:          Nick joins the lab as Engineering freshman. Welcome Nick!

October, 17 2019:    Our lab attends and presents at the 2019 BMES meeting in Philadelphia, PA

Sept, 30 2019:         Dammy joins the lab as BioE undergraduate student. Welcome Dammy!

August, 26 2019:     Dorota and Matt join the lab as Bioengineering PhD students. Welcome Dorota and Matt!  

August, 19 2019:     Alexis joins the lab as a research technician. Welcome Alexis!

May, 5 2019:           Yannis presented at the Great Lakes Breast Cancer Research Symposium in Columbus, OH

February, 14 2019:   Yannis presented at the UPMC Hillman Cancer Center Basic and Translational Research

                              Seminar Series in Pittsburgh, PA

November, 4 2018:   Yannis attended and presented at the 2018 Systems Approaches to Cancer Systems                                        Biology meeting in Woods Hole, MA


Department of Bioengineering, University of Pittsburgh

© 2020 Tumor Microenvironment Engineering (TME) lab

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