Engineering cell-cell interactions in cancer

We employ a quantitative approach that integrates microfluidics, systems biology modeling, and in vivo experiments to investigate the role of the tumor microenvironment on breast and ovarian cancer growth, metastasis and drug resistance.


The lab is growing and there are openings at the student, postdoc and research assistant levels. Our lab offers the opportunity to work at the forefront of cancer bioengineering, learn cutting edge techniques and collaborate with an interdisciplinary group of scientists and clinicians in the Cancer Center.

Video of invading breast carcinoma cells in a 3D microfluidic device (Zervantonakis et al)


Lab News

October, 17 2019:      Our lab attends and presents at the 2019 BMES meeting in Philadelphia, PA

August, 26 2019:       Dorota Jazwinska and Matt Poskus join the lab as Bioengineering PhD students. Welcome Dorota

                               and Matt!

August, 19 2019:       Alexis Scott joins the lab as a research technician. Welcome Alexis!

May, 5 2019:             Yannis presented at the Great Lakes Breast Cancer Research Symposium in Columbus, OH

February, 14 2019:     Yannis presented at the UPMC Hillman Cancer Center Basic and Translational Research

                                Seminar Series in Pittsburgh, PA

November, 4 2018:    Yannis attended and presented at the 2018 Systems Approaches to Cancer Systems Biology

                               meeting in Woods Hole, MA

October, 12 2018:      Yannis attended and presented at the 2018 BMES meeting in Atlanta, GA


Department of Bioengineering, University of Pittsburgh

© 2019 Tumor Microenvironment Engineering (TME) lab

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